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 NICOTINE

Cigarette Smoking

Although many people smoke because they believe cigarettes calm their nerves, smoking releases epinephrine, a hormone which creates physiological stress in the smoker, rather than relaxation. The use of tobacco is addictive. Most users develop tolerance for nicotine and need greater amounts to produce a desired effect. Smokers become physically and psychologically dependent and will suffer withdrawal symptoms including: changes in body temperature, heart rate, digestion, muscle tone, and appetite. Psychological symptoms include: irritability, anxiety, sleep disturbances, nervousness, headaches, fatigue, nausea, and cravings for tobacco that can last days, weeks, months, years, or an entire lifetime.

Risks associated with smoking cigarettes:

                   *********************

diminished or extinguished sense of smell and taste
frequent colds
smoker's cough
gastric ulcers
chronic bronchitis
increase in heart rate and blood pressure
premature and more abundant face wrinkles
emphysema
heart disease
stroke
cancer of the mouth, larynx, pharynx, esophagus, lungs, pancreas, cervix, uterus, and bladder

Cigarette smoking is perhaps the most devastating preventable cause of disease and premature death.

Smoking is particularly dangerous for teens because their bodies are still developing and changing and the 4,000 chemicals (including 200 known poisons) in cigarette smoke can adversely affect this process.

Cigarettes are highly addictive. One-third of young people who are just "experimenting" end up being addicted by the time they are 20.

The mode of action of the narcotic analgesics is still not fully understood. Recent research has determined that specific regions of the brain and spinal cord have an affinity for binding opiates, and the binding sites in the brain are in the same general areas where pain centers are believed to be. This research has also succeeded in isolating compounds, called enkephalins, that are produced in the body to reduce pain; the compounds consist of five amino acids. Apparently they can depress neurons throughout the central nervous system. They belong to a group of larger compounds called endorphins, consisting of many amino acids, that have also been isolated in the body and that are produced by the pituitary gland. Administration of endorphins, including the enkephalins, results in effects similar to those produced by opiates.

The discovery of a class of compounds that are specific antagonists to the action of the opiates has made it possible to treat opiate overdosage quickly and efficiently. The standard drug for this use is naloxone. Some of the antagonists also have opiatelike properties, and this has led to the introduction of a new class of analgesics, the mixed agonists-antagonists. It is hoped that these drugs will produce analgesia without euphoria, reducing their potential for abuse. The three drugs of this class approved so far in the U.S.—pentazocine, butorphanol, and nalbuphine—are as analgesic as morphine for many uses and induce little or no euphoria. All appear to have a lower abuse potential than morphine or propoxyphene.

For a great recovery rescource, visit: Nicotine Anonymous

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